5-Amino-1MQ is a small-molecule quinolinium inhibitor of nicotinamide N-methyltransferase (NNMT), supplied as a solid research material for controlled studies of enzyme inhibition, nicotinamide metabolism, methyl-donor pathways and cellular metabolic signalling.
Research material only
This material is not supplied as a medicine, treatment, supplement or consumer product. It is not for human or veterinary use, consumption or administration, and is not intended to diagnose, treat, cure or prevent any disease.
Compound overview
Research context
5-Amino-1MQ is the common shorthand for 5-amino-1-methylquinolinium, frequently studied as its iodide salt. NNMT catalyses methyl transfer from S-adenosyl-L-methionine to nicotinamide, producing 1-methylnicotinamide and S-adenosyl-L-homocysteine.
Published experimental work has examined quinolinium NNMT-inhibitor structure–activity relationships, enzyme selectivity, cellular metabolite responses, analytical measurement and diet-induced-obesity models in rodents. This evidence is predominantly preclinical and provides compound-level context only; it does not establish the identity, performance or suitability of the material supplied on this page.
Batch documentation
Independent analytical documentation is published where available for specific batches and variations. A result indicator appears only when a published record is available. Match the vial size and batch identifier to the corresponding report before relying on any result.
Supply and laboratory handling
- Supplied in the quantity selected above.
- Provided as a solid small-molecule material for laboratory research.
- Use calibrated equipment and an independently validated protocol appropriate to the intended study.
- Record the product designation, quantity, batch identifier and preparation conditions in the laboratory record.
Frequently asked questions
What is 5-Amino-1MQ?
5-Amino-1MQ is a quinolinium small molecule commonly studied as an inhibitor of nicotinamide N-methyltransferase.
Is 5-Amino-1MQ a peptide?
No. It is a small-molecule quinolinium compound rather than an amino-acid peptide.
What is NNMT?
Nicotinamide N-methyltransferase is a cytosolic enzyme that transfers a methyl group from S-adenosyl-L-methionine to nicotinamide. It is studied in relation to nicotinamide, NAD+ and methyl-donor metabolism.
Which chemical form is referenced?
The overview refers to 5-amino-1-methylquinolinium iodide, with the reference formula C10H11IN2 and molecular mass of approximately 286.11 Da. Confirm the stated form against the applicable batch documentation.
What research is linked on this page?
The Research tab links to compound-identification data and published enzyme, structure–activity, analytical, cellular and rodent-model studies. These sources provide scientific context and are not product-performance claims.
Which quantities are available?
Current quantities and availability are shown in the selector above. This information updates with the product variations rather than being fixed in the description.
Are published laboratory results available?
Where a published batch record exists, a result indicator appears beside the applicable variation and the corresponding documentation is available on the lab-results page. No indicator means that no product-specific published result is currently displayed for that variation.
How should 5-Amino-1MQ be stored?
Protect sealed material from light, moisture and repeated temperature changes. After preparing a solution, store it refrigerated at 2–8°C where compatible with the validated laboratory protocol and documented solvent system.
Information reviewed 29 August 2026.
