SNAP-8 (acetyl octapeptide-3) is a synthetic eight-amino-acid peptide supplied for laboratory research and analytical applications. Published work includes peptide quantification and studies of formulated microneedle systems containing acetyl octapeptide-3.
Research material only This material is not supplied as a medicine, treatment, supplement or consumer product. It is not for human or veterinary use, consumption or administration, and is not intended to diagnose, treat, cure or prevent any disease.
Compound overview
Compound nameSNAP-8
Alternative nameAcetyl octapeptide-3
Compound classSynthetic peptide
Peptide length8 amino acids
Reference sequenceAc-EEMQRRAD-NH₂
Terminal modificationsN-acetylated; C-terminal amide
Research context
SNAP-8 is an extended relative of the acetyl hexapeptide commonly known as Argireline. It is discussed in the literature in relation to SNAP-25/SNARE-associated signalling and cosmetic formulation research. It is not botulinum toxin, and these mechanistic descriptions do not establish therapeutic equivalence.
Direct published research includes an LC-MS/MS analytical method and clinical evaluations of multi-ingredient microneedle patches. Those formulation studies cannot isolate the contribution of SNAP-8 or establish the safety or efficacy of this standalone research material. See the Research tab for linked publications and study-specific limitations.
Batch documentation
Independent analytical documentation is published where available for specific batches and variations. A result indicator appears only when a published record is available. Match the compound, vial size and batch identifier to the corresponding report before relying on any result.
Supply and laboratory handling
- Supplied in the vial size selected above.
- Provided as a lyophilised research material.
- Keep the vial sealed and protected from moisture, heat and direct light.
- Use suitable laboratory controls and independently verify identity and concentration for the intended experimental model.
Frequently asked questions
What is SNAP-8?
SNAP-8 is the name commonly used for acetyl octapeptide-3, a synthetic peptide containing eight amino acids with an acetylated N-terminus and amidated C-terminus.
Is SNAP-8 the same as Argireline?
No. SNAP-8 is an octapeptide, while Argireline is an acetyl hexapeptide. The related compounds differ in peptide length and should not be treated as interchangeable research materials.
Does the published research test this vial?
No. The linked literature concerns analytical methods or specific experimental formulations. It does not verify this product or its batches, and results from multi-ingredient formulations cannot be attributed to SNAP-8 alone.
Which vial size will I receive?
The supplied quantity is determined by the variation selected above. This description applies across available vial sizes.
Where can I find batch testing?
Check the product testing information for a published report matching the selected variation and batch. Published research is separate from batch-specific analytical documentation.
How should laboratory storage be determined?
Keep the material sealed and protected from moisture, heat and light. Follow batch documentation and the requirements of the validated laboratory protocol; solution stability depends on the experimental conditions.
Information reviewed 27 September 2026. Reference: Shin et al., 2024.
Batch-specific analytical documentation
Independent analytical results are published for selected Havoc Labs products, vial sizes and batches. The result attached to one variation must not be treated as evidence for a different size or batch.
- Result available: a published report is available for the marked variation.
- Test pending: a sample has been submitted, but no completed result is being claimed.
- No indicator: no product-specific result is currently displayed for that variation.
Check the identifiers
Always match the compound, vial size and batch reference on the product to the corresponding laboratory record. Where the laboratory provides an independent verification facility, use it to confirm the report.
Browse published lab results →
Storage and stability
Storage requirements can vary by compound, physical form, intended storage duration and batch. Follow the lot-specific documentation and your laboratory’s validated procedure wherever these are available.
| Form |
Suggested storage |
Important note |
| Sealed lyophilised material |
Keep in a cool, dry place, refrigerated at 2–8°C or frozen, as appropriate for the compound and intended storage period. |
Keep sealed, dry and protected from direct light. Follow compound- and batch-specific documentation and avoid repeated temperature cycling. |
| Reconstituted solution |
Refrigerate at 2–8°C unless the applicable laboratory protocol specifies otherwise. |
Stability depends on the preparation conditions, solvent, concentration, container and handling. No universal storage period is claimed. |
No universal shelf-life is claimed
Do not assume a fixed expiry or prepared-solution storage period unless it is supported by relevant stability data or batch documentation. Where a lot-specific document gives different instructions, that document takes precedence.
Published research
The publications below concern acetyl octapeptide-3 (SNAP-8). They distinguish analytical characterisation from research on formulated products; none constitutes testing of this vial or evidence for administering this research material.
- Ji M et al. (2020). Method development for acetyl octapeptide-3 analysis by liquid chromatography-tandem mass spectrometry. Journal of Analytical Science and Technology 11:34.
Developed and validated an LC-MS/MS method to quantify SNAP-8, including application to a biodegradable patch matrix. Useful analytical context, not an efficacy or safety study; matrix effects must be considered when interpreting measurements.
DOI: 10.1186/s40543-020-00232-8 · Open-access article
- Avcil M et al. (2020). Efficacy of bioactive peptides loaded on hyaluronic acid microneedle patches: A monocentric clinical study. Journal of Cosmetic Dermatology 19(2):328–337.
A 12-week study evaluated skin measurements and tolerability of a hyaluronic acid patch containing acetyl octapeptide-3, other peptides, adenosine and seaweed extracts. Findings concern the complete formulation and do not isolate the contribution of SNAP-8.
DOI: 10.1111/jocd.13009 · PubMed record
- Shin JY et al. (2024). Clinical Safety and Efficacy Evaluation of a Dissolving Microneedle Patch Having Dual Anti-Wrinkle Effects With Safe and Long-Term Activities. Annals of Dermatology 36(4):215–224.
A 28-day comparative study in 24 subjects evaluated a multi-ingredient patch against a hyaluronic-acid-only patch. The test formulation included acetyl octapeptide-3, a vitamin C derivative and sodium cyclic lysophosphatidic acid. Its small sample, short follow-up and combined ingredients limit conclusions about standalone SNAP-8.
DOI: 10.5021/ad.23.136 · Open-access article
Literature is not batch evidence Published studies do not establish the identity, purity, content or suitability of any supplied batch. Formulation findings cannot be transferred to this standalone research material. Research use only; not for human or veterinary use.
References reviewed 27 September 2026.
