MOTS-c is a 16-amino-acid mitochondrial-derived peptide encoded within a short open reading frame of mitochondrial 12S rRNA. It is supplied as a lyophilised research material for controlled studies of metabolic signalling, cellular stress responses and mitonuclear communication.
Research material only
This material is not supplied as a medicine, treatment, supplement or consumer product. It is not for human or veterinary use, consumption or administration, and is not intended to diagnose, treat, cure or prevent any disease.
Compound overview
Research context
MOTS-c was identified as a mitochondrial-genome-associated signalling peptide. Published experimental studies have examined its relationship with folate and purine metabolism, AMPK-associated signalling and cellular metabolic responses. Other work has investigated its movement to the nucleus during metabolic stress and its effects on nuclear gene expression.
These findings describe the cell, animal and analytical models used by the cited researchers. They do not establish the identity, purity, performance or suitability of the material supplied on this page, and experimental findings must not be interpreted as consumer or clinical claims.
Batch documentation
Independent analytical documentation is published where available for specific batches and variations. A result indicator appears only when a published record is available. Match the product, stated mass and batch identifier to the corresponding report before relying on any result.
View available MOTS-c lab results →
Supply and laboratory handling
- Supplied in the vial size selected above.
- Keep the sealed lyophilised vial dry and protected from direct light.
- A cool, dry place, refrigerator or freezer may be used according to the intended storage duration and your laboratory’s validated procedure.
- Use clean laboratory technique and equipment appropriate to the intended analytical method.
- Follow the lot-specific documentation and your laboratory’s validated handling and storage procedures.
- Avoid repeated temperature cycling and unnecessary exposure to moisture.
Where a batch document or supplier specification gives different instructions, the lot-specific document takes precedence.
Frequently asked questions
What is MOTS-c?
MOTS-c is a 16-amino-acid mitochondrial-derived peptide encoded within a short open reading frame associated with mitochondrial 12S rRNA. It is studied in experimental models of cellular metabolism, stress signalling and communication between mitochondrial and nuclear systems.
Is MOTS-c supplied as a medicine?
No. This product is supplied only as a laboratory research material and is not for human or veterinary use, consumption or administration.
Which vial sizes are available?
Current vial sizes, stock, pre-order status, pricing and any batch-documentation indicators are shown in the variation selector above.
Does every vial size have a published laboratory result?
No. Results are available only for the selected batches and variations marked with a result indicator. Always check that the product, stated mass and batch identifier match the report.
How should the material be stored?
Keep the sealed lyophilised material dry and protected from light. A cool, dry place, refrigerator or freezer may be used according to the intended storage duration and your laboratory’s validated procedure. Avoid repeated temperature cycling and moisture exposure. No universal shelf-life is stated unless it is supported by batch documentation.
Information reviewed: 29 August 2026.
